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Article

Shared proteomic landscape between arteriosclerosis and cardiovascular endpoints: a Mendelian randomization and observational study integrating AlphaFold3 for structural prediction

2025-05-16

Abstract excerpt

<h4>Background</h4> Atherosclerosis and arteriosclerosis are major contributors to cardiovascular disease (CVD), yet their shared and distinct molecular underpinnings remain incompletely understood. This study integrates proteomics, Bayesian colocalization, and Mendelian randomization (MR), and structural modelling to explore the shared and distinct plasma proteome associated with arteriosclerosis and atherosclero...

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Literature Corpus work
f59f887f-5039-50dd-bd38-b7e52675d69a
DOI
10.1101/2025.05.15.25327712
Open publication

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Shared proteomic landscape between arteriosclerosis and cardiovascular endpoints: a Mendelian randomization and observational study integrating AlphaFold3 for structural predictionDOI 10.1101/2025.05.15.25327712
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