Article

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

2020-04-06

Abstract excerpt

Circulating proteins are vital in human health and disease and are frequently used as biomarkers for clinical decision-making or as targets for pharmacological intervention. By mapping and replicating protein quantitative trait loci (pQTL) for 90 cardiovascular proteins in over 30,000 individuals, we identified 467 pQTLs for 85 proteins. The pQTLs were used in combination with other sources of information to evalu...

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Literature Corpus work: 2d3c9561-14c2-5dd6-95e8-4fc8391fe21f
DOI: 10.1101/2020.04.03.023804

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