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Polygenic analyses show important differences between MDD symptoms collected using PHQ9 and CIDI-SF

2023-03-01

Abstract excerpt

Symptoms of Major Depressive Disorder (MDD) are commonly assessed using self-rating instruments like the Patient Health Questionnaire 9 (PHQ9, for current symptoms), and the Composite International Diagnostic Interview Short-Form (CIDI-SF, for lifetime worst-episode symptoms). Using data from the UKBiobank, we show that corresponding symptoms endorsed through PHQ9 and CIDI-SF have low to moderate genetic correlati...

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Literature Corpus work
fedac589-a94d-589c-a6b7-765e110e2824
DOI
10.1101/2023.02.27.23286527
Open publication

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