Article

Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

2019-05-08

Abstract excerpt

Recent developments in stem cell biology have enabled the study of cell fate decisions in early human development that are impossible to study in vivo . However, understanding how development varies across individuals and, in particular, the influence of common genetic variants during this process has not been characterised. Here, we exploit human iPS cell lines from 125 donors, a pooled experimental design, and...

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Literature Corpus work: fe29f167-4d04-5e93-a518-ce6bda8eb10f
DOI: 10.1101/630996

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