Article

Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation

2020-05-22

Abstract excerpt

Common genetic variants can have profound effects on cellular function, but studying these effects in primary human tissue samples and during development is challenging. Human induced pluripotent stem cell (iPSC) technology holds great promise for assessing these effects across different differentiation contexts. Here, we use an efficient pooling strategy to differentiate 215 iPS cell lines towards a midbrain neur...

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Literature Corpus work: a61676a9-a5bd-5c5c-96ce-cfef38134bc9
DOI: 10.1101/2020.05.21.103820

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