Article

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast

2017-11-21

Abstract excerpt

Single-cell profiling techniques create opportunities to delineate cell fate progression in mammalian development. Recent studies provide transcriptome data from human preimplantation embryos, in total comprising nearly 2000 individual cells. Interpretation of these data is confounded by biological factors such as variable embryo staging and cell-type ambiguity, as well as technical challenges in the collective an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f7baebae-5f43-57e8-8d8b-6b5885b841e1
DOI: 10.1101/222760

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblastDOI 10.1101/222760Read

A single-cell transcriptome atlas of human early embryogenesisSemantic proximity Read

Defining early human developmental identity: A curated, cross-platform marker frameworkSemantic proximity Read

The selection arena in early human blastocysts resolves the pluripotent inner cell massSemantic proximity Read

Systematic evaluation of blastoid models of early human developmentSemantic proximity Read

A spatially resolved single cell atlas of human gastrulationSemantic proximity Read

Single-cell transcriptomic characterization of a gastrulating human embryoSemantic proximity Read

Spatiotemporal transcriptome atlas of human embryos after gastrulation.Semantic proximity Read

Molecular signatures associated with successful implantation of the human blastocystSemantic proximity Read

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloidsSemantic proximity Read

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloidsSemantic proximity Read

The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution.Semantic proximity Read

Single-cell analysis of shared signatures and transcriptional diversity during zebrafish developmentSemantic proximity Read