Article

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

2020-06-21

Abstract excerpt

The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) - cells that can be differentiated into any cell type of the three germ layers - has provided a foundation for in vitro human disease modelling 1,2 , drug development 1,2 , and population genetics studies 3,4 . In the majority of instances, the expression levels of genes, plays a critical role in contributing to dise...

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Literature Corpus work: 3e8a07d8-52ae-56f5-b144-4be3147285cd
DOI: 10.1101/2020.06.21.163766

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