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Endothelial Prolyl Hydroxylase 3 Mitigates Maladaptive Inflammation to Promote Post-Ischemic Kidney Repair

2025-04-22

Abstract excerpt

<h4>ABSTRACT</h4> Acute kidney injury (AKI) is a major health concern and well-established risk factor for the development of chronic kidney disease (CKD). Tissue hypoxia is a prominent feature of the injured kidney that shapes the biological behavior of parenchymal and immune cells. Endothelial cells have important immunomodulatory roles, but the impact of dysregulated oxygen sensing on their responses remains p...

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Literature Corpus work
fe17992e-9c75-5a1b-85b5-4de29e0a7362
DOI
10.1101/2025.04.21.649850
Open publication

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Endothelial Prolyl Hydroxylase 3 Mitigates Maladaptive Inflammation to Promote Post-Ischemic Kidney RepairDOI 10.1101/2025.04.21.649850
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