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Recent advances in understanding of chronic kidney disease

4 Nov 2015

Abstract excerpt

Chronic kidney disease (CKD) is defined as any condition that causes reduced kidney function over a period of time. Fibrosis, tubular atrophy and interstitial inflammation are the hallmark of pathological features in CKD. Regardless of initial insult, CKD has some common pathways leading CKD to end-stage kidney disease, including hypoxia in the tubulointerstitium and proteinuria. Recent advances in genome editing...

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PMID: 26937272
DOI: 10.12688/f1000research.6970.1

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