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Article

Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion

20 Sept 2017

Abstract excerpt

Though an acute kidney injury (AKI) episode is associated with an increased risk of chronic kidney disease (CKD), the mechanisms determining the transition from acute to irreversible chronic injury are not well understood. To extend our understanding of renal repair, and its limits, we performed a detailed molecular characterization of a murine ischemia/reperfusion injury (IRI) model for 12 months after injury....

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PMID: 28931758
DOI: 10.1172/jci.insight.94716

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