Article

KIR*BLOOM: Accurate KIR genotyping using a new copy number-aware integrated genotype likelihood framework

2026-04-20

Abstract excerpt

Killer-cell immunoglobulin-like receptor (KIR) genes, key modulators of natural killer (NK) cell activity, play critical roles in immune response and disease susceptibility. Accurate KIR genotyping from short-read sequencing data remains challenging because of high sequence similarity among genes, extensive copy number variation, and substantial allelic diversity. Here, we present KIR*BLOOM, a likelihood-based app...

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Literature Corpus work: 28caf689-d688-5e59-9ec8-0597dd12bdf7
DOI: 10.64898/2026.04.15.718735

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