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Article

Graph-KIR: graph-based KIR copy number estimation and allele calling using short-read sequencing data.

Bioinformatics (Oxford, England) - 2 Jul 2026

Lin Hong-Ye, Wang Ting-Jian, Chang Ting-Yu, Chuang Hui-Wen, Hung Tsung-Kai, Lin Ching-Jim, Hsu Jacob Shujui, Hsu Chia-Lang, Yang Ya-Chien, Chen Pei-Lung, Chen Chien-Yu

Abstract excerpt

MOTIVATION: The Killer-cell Immunoglobulin-like Receptor (KIR) is a highly polymorphic region in the human genome, associated with autoimmune diseases and organ transplantation. The sequences of KIR genes are highly similar among star alleles as well as in between individual genes, with the copy number of each KIR gene typically ranging from 0 to 4. In this study, we introduce Graph-KIR, a tool designed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42478776
DOI: 10.1093/bioinformatics/btag521
PMCID: PMC13423236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Graph-KIR: graph-based KIR copy number estimation and allele calling using short-read sequencing data.PMID 42478776Read ↗

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