Article

Single-molecule visualization of sequence-specific RNA binding by a designer PPR protein

2024-04-22

Abstract excerpt

Pentatricopeptide repeat (PPR) proteins are a large family of modular RNA-binding proteins that recognize specific ssRNA target sequences. There is significant interest in developing ‘designer’ PPRs for use in diagnostics or as tools to detect and localize target RNA sequences. However, it is unclear how PPRs search for target sequences within complex transcriptomes and current models to predict PPR binding sites...

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Literature Corpus work: fd5ec191-1d4c-58e7-9e92-ae9fceabdff3
DOI: 10.1101/2024.04.22.590477

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