Article
RNA biochemistry. Determination of in vivo target search kinetics of regulatory noncoding RNA.
Science (New York, N.Y.) - 20 Mar 2015
Fei Jingyi, Singh Digvijay, Zhang Qiucen, Park Seongjin, Balasubramanian Divya, Golding Ido, Vanderpool Carin K, Ha Taekjip
Abstract excerpt
Base-pairing interactions between nucleic acids mediate target recognition in many biological processes. We developed a super-resolution imaging and modeling platform that enabled the in vivo determination of base pairing-mediated target recognition kinetics. We examined a stress-induced bacteria...
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