Article
The organization of RNA contacts by PTB for regulation of FAS splicing.
Nucleic acids research - 1 Jul 2014
Mickleburgh Ian, Kafasla Panagiota, Cherny Dmitry, Llorian Miriam, Curry Stephen, Jackson Richard J, Smith Christopher W J
Abstract excerpt
Post-transcriptional steps of gene expression are regulated by RNA binding proteins. Major progress has been made in characterizing RNA-protein interactions, from high resolution structures to transcriptome-wide profiling. Due to the inherent technical challenges, less attention has been paid to the way in which proteins with multiple RNA binding domains engage with target RNAs. We have investigated how the four...
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