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Modular construction of bispecific antibodies through bioconjugation for T cell-based immunotherapy

2026-01-05

Abstract excerpt

<title>Abstract</title> <p>Bispecific antibodies (bsAbs) represent a groundbreaking advance in antibody engineering, overcoming therapeutic limitations of monoclonal antibodies through dual-targeting capabilities. However, their clinical translation is often hindered by structural and manufacturing complexities. In this study, we developed a modular bsAb platform utilizing the SpyCatcher-SpyTag site-specific coup...

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Identifiers and source

Literature Corpus work
fce78fb8-1f9e-5d29-925d-c548c700153e
DOI
10.21203/rs.3.rs-8371642/v1
Open publication

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Modular construction of bispecific antibodies through bioconjugation for T cell-based immunotherapyDOI 10.21203/rs.3.rs-8371642/v1
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