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A CHIMERIC RECEPTOR ENABLING ANTIBODY-GUIDED RETARGETING OF CAR T- CELLS

2026-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Chimeric antigen receptor (CAR)-T cell therapies achieve remarkable responses in hematologic malignancies but are limited by target heterogeneity and antigen escape; therapeutic antibodies offer flexible targeting yet cannot leverage T-cell effector function. Integrating CAR-T cell potency with antibody targeting adaptability could expand the clinical reach of cellular immunotherapy. We engineer...

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Literature Corpus work
3d2d8782-54d9-5503-945d-da25a278f4ec
DOI
10.64898/2026.04.27.720976
Open publication

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