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Principles and Current Clinical Landscape of Multispecific Antibodies against Cancer

26 May 2021

Abstract excerpt

Building upon the resounding therapeutic success of monoclonal antibodies, and supported by accelerating progress in engineering methods, the field of multispecific therapeutic antibodies is growing rapidly. Over 140 different molecules are currently in clinical testing, with excellent results in recent phase 1-3 clinical trials for several of them. Multivalent bispecific IgG-modified formats predominate today,...

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PMID: 34073188
DOI: 10.3390/ijms22115632

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