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Article

A high throughput bispecific antibody discovery pipeline

2021-09-08

Abstract excerpt

Bispecific antibodies (BsAbs) represent an emerging class of immunotherapy but inefficiency in the current BsAb discovery paradigm has limited their broad clinical availability. Here we report a high throughput, agnostic, single-cell-based BsAb functional screening pipeline, comprising molecular and cell engineering for efficient generation of BsAb library cells, followed by functional interrogation at the single-...

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Identifiers and source

Literature Corpus work
8bfcb92e-1b70-5737-9c24-e3fee59010a9
DOI
10.1101/2021.09.07.459213
Open publication

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A high throughput bispecific antibody discovery pipelineDOI 10.1101/2021.09.07.459213
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