Article

DNA-mediated assembly of multi-specific antibodies for T cell engaging and tumor killing

2019-09-26

Abstract excerpt

Targeting T-cells against cancer cells is a direct means of treating cancer, and already showed great responses in clinical treatment of B-cell malignancies. A simple way to redirect T-cells to cancer cells is using multi-specific antibody (MsAb) that contains different arms for specifically “grabbing” the T-cells and cancer cells; as such, the T-cells are activated upon target engagement and the killing begins. H...

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Literature Corpus work: 5c02986a-2d6e-5e10-b4ac-3c75b492c9cd
DOI: 10.1101/782862

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