Article

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

2016-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia (SCZ), bipolar disorder (BD) and recurrent major depressive disorder (rMDD) are common psychiatric illnesses. All have been associated with lower cognitive ability, and show evidence of genetic overlap and substantial evidence of pleiotropy with cognitive function and neuroticism. Disrupted in schizophrenia 1 (DISC1) protein directly interacts with a large set of proteins (DISC1 I...

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Literature Corpus work: fcaf1175-1ef9-52b5-ad75-6f527b4546dc
DOI: 10.1101/083816

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