Article
Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes.
Molecular psychiatry - 1 Nov 2011
Carless M A, Glahn D C, Johnson M P, Curran J E, Bozaoglu K, Dyer T D, Winkler A M, Cole S A, Almasy L, MacCluer J W, Duggirala R, Moses E K, Göring H H H, Blangero J
Abstract excerpt
Although disrupted in schizophrenia 1 (DISC1) has been implicated in many psychiatric disorders, including schizophrenia, bipolar disorder, schizoaffective disorder and major depression, its biological role in these disorders is unclear. To better understand this gene and its role in psychiatric disease, we conducted transcriptional profiling and genome-wide association analysis in 1232 pedigreed Mexican-American...
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