Article
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
Molecular psychiatry - 1 Jun 2014
Thomson P A, Parla J S, McRae A F, Kramer M, Ramakrishnan K, Yao J, Soares D C, McCarthy S, Morris S W, Cardone L, Cass S, Ghiban E, Hennah W, Evans K L, Rebolini D, Millar J K, Harris S E, Starr J M, MacIntyre D J, McIntosh A M, Watson J D, Deary I J, Visscher P M, Blackwood D H, McCombie W R, Porteous D J
Abstract excerpt
A balanced t(1;11) translocation that transects the Disrupted in schizophrenia 1 (DISC1) gene shows genome-wide significant linkage for schizophrenia and recurrent major depressive disorder (rMDD) in a single large Scottish family, but genome-wide and exome sequencing-based association studies ha...
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