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Article

The DISC locus in psychiatric illness.

Molecular psychiatry - 1 Jan 2008

Chubb J E, Bradshaw N J, Soares D C, Porteous D J, Millar J K

Abstract excerpt

The DISC locus is located at the breakpoint of a balanced t(1;11) chromosomal translocation in a large and unique Scottish family. This translocation segregates in a highly statistically significant manner with a broad diagnosis of psychiatric illness, including schizophrenia, bipolar disorder and major depression, as well as with a narrow diagnosis of schizophrenia alone. Two novel genes were identified at this...

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Source

Identifiers

PMID: 17912248
DOI: 10.1038/sj.mp.4002106

Genes

DISC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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