Article

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with signatures from post mortem adult brains

2017-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Whereas highly penetrant variants have proven well-suited to human induced pluripotent stem cell (hiPSC)-based models, the power of hiPSC-based studies to resolve the much smaller effects of common variants within the size of cohorts that can be realistically assembled remains uncertain. In developing a large case/control schizophrenia (SZ) hiPSC-derived cohort of neural progenitor cells and neu...

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Literature Corpus work: fc5b2d83-51b4-5f3f-81f3-d518a0f3d322
DOI: 10.1101/185546

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