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Article

Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia.

Stem cells (Dayton, Ohio) - 1 Dec 2011

Brennand Kristen J, Gage Fred H

Abstract excerpt

Schizophrenia (SCZD) is a heritable developmental disorder. Although the molecular mechanism of disease remains unclear, insights into the disorder have been made through a vast array of experimental techniques. Together, magnetic resonance brain imaging, pharmacological, and post-mortem pathological studies have observed decreased brain volume, aberrant neurotransmitter signaling, reduced dendritic arborization,...

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Identifiers

PMID: 22009633
DOI: 10.1002/stem.762
PMCID: PMC3381343

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