Article

Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia

2020-07-04

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia (SZ) is a common and debilitating psychiatric disorder with limited effective treatment options. Although highly heritable, risk for this polygenic disorder depends on the complex interplay of hundreds of common and rare variants. Translating the growing list of genetic loci significantly associated with disease into medically actionable information remains an important challenge....

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Literature Corpus work: c7ac000c-9bb1-5203-be09-35449c3ad092
DOI: 10.1101/2020.07.04.185348

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