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Article

New considerations for hiPSC-based models of neuropsychiatric disorders.

Molecular psychiatry - 1 Jan 2019

Hoffman Gabriel E, Schrode Nadine, Flaherty Erin, Brennand Kristen J

Abstract excerpt

The development of human-induced pluripotent stem cells (hiPSCs) has made possible patient-specific modeling across the spectrum of human disease. Here, we discuss recent advances in psychiatric genomics and post-mortem studies that provide critical insights concerning cell-type composition and sample size that should be considered when designing hiPSC-based studies of complex genetic disease. We review recent...

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Identifiers

PMID: 29483625
DOI: 10.1038/s41380-018-0029-1
PMCID: PMC6109625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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