Article

Leveraging phenotypic variability to identify genetic interactions in human phenotypes

2020-07-28

Abstract excerpt

While thousands of loci have been associated with human phenotypes, the role of gene-environment (GxE) interactions in determining individual risk of human diseases remains unclear. This is partly due to the severe erosion of statistical power resulting from the massive number of statistical tests required to detect such interactions. Here, we focus on improving the power of GxE tests by developing a statistical f...

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Literature Corpus work: fa373de8-7fcb-5d4f-98db-ea0d44ce3f6e
DOI: 10.1101/2020.07.28.225730

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