Article

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

2019-01-14

Abstract excerpt

Genotype-by-environment interaction (GEI) is a fundamental component in understanding complex trait variation. However, it remains challenging to identify genetic variants with GEI effects in humans largely because of the small effect sizes and the difficulty of monitoring environmental fluctuations. Here, we demonstrate that GEI can be inferred from genetic variants associated with phenotypic variability in a lar...

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Literature Corpus work: 45107153-3e21-5134-a96c-d54d47c0067c
DOI: 10.1101/519538

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