Article

Joint modeling of genomic and exposomic data reveals a substantial GxE component in type 2 diabetes etiology

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>Understanding the relative contribution of genetic and environmental factors and their interactions is important in mapping complex diseases. We integrated genomic data with unprecedented questionnaire-based exposure data from the Personalized Environment and Genes Study (PEGS) to dissect the etiology of type 2 diabetes and two exemplar traits, namely height and BMI. We estimated the ph...

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Literature Corpus work: 66318290-2776-5d6d-b5a8-a27d3da74abe
DOI: 10.21203/rs.3.rs-3832061/v1

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