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Article

Modeling Interaction and Dispersion Effects in the Analysis of Gene-by-Environment Interaction.

Behavior genetics - 1 Jan 2022

Domingue Benjamin W, Kanopka Klint, Mallard Travis T, Trejo Sam, Tucker-Drob Elliot M

Abstract excerpt

Genotype-by-environment interaction (GxE) studies probe heterogeneity in response to risk factors or interventions. Popular methods for estimation of GxE examine multiplicative interactions between individual genetic and environmental measures. However, risk factors and interventions may modulate the total variance of an epidemiological outcome that itself represents the aggregation of many other etiological...

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Identifiers

PMID: 34855050
DOI: 10.1007/s10519-021-10090-8
PMCID: PMC8958844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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