Article

Musashi1 and its short C-terminal variants regulate pluripotency states in embryonic stem cells

2022-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Musashi1 (MSI1) is a marker for adult stem cells, but little is known for its expression and function in pluripotent stem cells (PSCs). Here we report that MSI1 is expressed in embryonic stem cells (ESCs) and is required for pluripotency maintenance. We found that there exit short c-terminal MSI1 variants (MSI1-C, hMSI1 272-362 or mMSI1 138-362 ) in naïve but not primed ESCs. When overexpresse...

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Identifiers and source

Literature Corpus work: f9e452c1-1d23-548c-9c39-bd1b110cdb06
DOI: 10.1101/2022.05.02.490263

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