Article

Variant U1 snRNAs contribute to cell cycle and differentiation control of human iPS cells

2025-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Maintenance of stem cell identity as well as differentiation of stem cells into the various lineages requires intricate regulation of gene expression. Despite intensive research, our understanding of these regulatory networks remains incomplete. Here, we focus on the understudied paralogs of the U1 small nuclear RNA (snRNA) gene known as variant U1 (vU1) snRNAs. By generating isogenic knockout l...

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Literature Corpus work: cd6565bd-ccc9-5a91-b79b-370444044175
DOI: 10.1101/2025.09.14.676199

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