Article

Alternative splicing links histone modifications to stem cell fate decision

2017-09-01

Abstract excerpt

<h4>Background</h4> Understanding the embryonic stem cell (ESC) fate decision between self-renewal and proper differentiation is important for developmental biology and regenerative medicine. Attention has focused on mechanisms involving histone modifications, alternative pre-mRNA splicing, and cell-cycle progression. However, their intricate interrelations and joint contributions to ESC fate decision remain uncl...

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Literature Corpus work: 3644286b-7a86-515b-ab05-e691cd3d5568
DOI: 10.1101/181875

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