Article

Comparative RNAi Screens in Isogenic Human Stem Cells Reveal <i>SMARCA4</i> as a Differential Regulator

2018-12-19

Abstract excerpt

<h4>SUMMARY</h4> Large-scale RNAi screens are a powerful approach to identify functions of genes in a cell-type specific manner. For model organisms, genetically identical (isogenic) cells from different cell-types are readily available, making comparative studies meaningful. For humans, however, screening isogenic cells is not straightforward. Here, we show that RNAi screens are possible in genetically identical...

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Literature Corpus work: 7b011718-2ae0-5487-8f68-c6cb90c25937
DOI: 10.1101/500181

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