Article

KLF7 is a general inducer of human pluripotency

2023-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Pluripotency is the capacity to give rise to all differentiated cells of the body and the germ line and is governed by a self-reinforcing network of transcription factors. The forced expression of only some of these factors enables the reprogramming of somatic cells to pluripotency. In murine cells, several kruppel-like factors (KLFs) have been identified as stabilisers and inducers of pluripote...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6355938-1106-5c30-a943-9a9d25bf6faf
DOI: 10.1101/2023.09.06.556189

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

KLF7 is a general inducer of human pluripotencyDOI 10.1101/2023.09.06.556189Read

KLF17 promotes human naïve pluripotency but is not required for its establishmentSemantic proximity Read

Mechanistic insights into reprogramming to induced pluripotencySemantic proximity Read

Hic2 fast-tracks iPS cell generation by suppressing KLF4-dependent epidermal detourSemantic proximity Read

The occurrence and development of induced pluripotent stem cellsSemantic proximity Read

Capture of mouse and human stem cells with features of formative pluripotencySemantic proximity Read

Human Embryonic Stem Cells: An In Vitro Model to Study Mechanisms Controlling Pluripotency in Early Mammalian DevelopmentSemantic proximity Read

Reconstitution of Pluripotency from Mouse Fibroblast through Sall4 OverexpressionSemantic proximity Read

[Induced pluripotent stem cells. A new resource in modern medicine].Semantic proximity Read

Upregulation of the lncRNA <i>XACT</i> sustains pluripotency, blocks lineage specification, and drives germ cell tumor-like transcriptional programs in human pluripotent stem cellsSemantic proximity Read

Human Induced Pluripotent Stem Cells: The Past, Present, and FutureSemantic proximity Read

The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells.Semantic proximity Read

Deciphering the mRNA-lncRNA-miRNA interaction landscape in human pluripotencySemantic proximity Read