Article

Optical activation of TrkB receptors

2019-12-15

Abstract excerpt

Brain-derived neurotrophic factor (BDNF), via activation of tropomyosin receptor kinase B (TrkB), plays a critical role in neuronal proliferation, differentiation, survival, and death. Dysregulation of TrkB signaling is implicated in neurodegenerative disorders and cancers. Precise activation of TrkB receptors with spatial and temporal resolution is greatly desired to study the dynamic nature of TrkB signaling and...

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Identifiers and source

Literature Corpus work: f96b59a8-2a39-5f61-bee2-18c6de815637
DOI: 10.1101/2019.12.15.876722

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