Article

A monogenic and fast-responding Light-Inducible Cre recombinase as a novel optogenetic switch

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Optogenetics enables genome manipulations with high spatiotemporal resolution, opening exciting possibilities for fundamental and applied biological research. Here, we report the development of LiCre, a novel light-inducible Cre recombinase. LiCre is made of a single flavin-containing protein comprising the asLOV2 photoreceptor domain of Avena sativa fused to a Cre variant carrying destabilizin...

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Literature Corpus work: d97b657f-db7b-5a27-91da-c995bc077107
DOI: 10.1101/2020.06.04.132548

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