Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics.

ACS synthetic biology - 18 Sept 2020

Mukherjee Abhirup, Sudrik Chaitanya, Hu Yuge, Arha Manish, Stathos Mark, Baek Jieung, Schaffer David V, Kane Ravi S

Abstract excerpt

The field of optogenetics uses genetically encoded photoswitches to modulate biological phenomena with high spatiotemporal resolution. We report a set of rationally designed optogenetic photoswitches that use the photolyase homology region of A. thaliana cryptochrome 2 (Cry2PHR) as a building block and exhibit highly efficient and tunable clustering in a blue-light dependent manner. CL6mN (Cry2-mCherry-LRP6c with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cryptochromes
Share to Half-Life

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Low Density Lipoprotein Receptor-Related Protein-6

Share to Luminescent Proteins

Share to Microscopy, Confocal

Share to Optogenetics

Share to Red Fluorescent Protein

Share to Wnt Signaling Pathway

Source

Identifiers

PMID: 32794731
DOI: 10.1021/acssynbio.0c00362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics.PMID 32794731Read ↗

An optimized optogenetic clustering tool for probing protein interaction and function.Semantic proximity Read ↗

Single-component optogenetic control enables human portrait formation in cellsSemantic proximity Read ↗

PHOTACs Enable Optical Control of Protein DegradationSemantic proximity Read ↗

A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseasesSemantic proximity Read ↗

Linear motifs in the C-terminus of D. melanogaster cryptochrome.Semantic proximity Read ↗

TULIPs: tunable, light-controlled interacting protein tags for cell biology.Semantic proximity Read ↗

Enhancing the performance of Magnets photosensors.Semantic proximity Read ↗

Reaction mechanism of Drosophila cryptochrome.Semantic proximity Read ↗

Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis.Semantic proximity Read ↗

Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning.Semantic proximity Read ↗

Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception.Semantic proximity Read ↗

Cyanobacteriochrome-based photoswitchable adenylyl cyclases (cPACs) for broad spectrum light regulation of cAMP levels in cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.