Article

Direct imaging of anthrax intoxication in animals reveals shared and individual functions of CMG-2 and TEM-8 in cellular toxin entry

2021-01-22

Abstract excerpt

<h4>SUMMARY</h4> The virulence of Bacillus anthracis is linked to the secretion of anthrax lethal toxin and anthrax edema toxin. These binary toxins consist of a common cell-binding moiety, protective antigen (PA), and the enzymatic moieties, lethal factor (LF) and edema factor (EF). PA binds either of two specific cell surface receptors, capillary morphogenesis protein-2 (CMG-2) or tumor endothelial marker-8 (T...

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Literature Corpus work: f80d2229-5c33-5760-8ad3-a8d111602ab8
DOI: 10.1101/2021.01.22.427304

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