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Article

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis.

Matrix biology : journal of the International Society for Matrix Biology - 1 Mar 2015

Besschetnova Tatiana Y, Ichimura Takaharu, Katebi Negin, St Croix Brad, Bonventre Joseph V, Olsen Bjorn R

Abstract excerpt

It is well known that angiogenesis is linked to fibrotic processes in fibroproliferative diseases, but insights into pathophysiological processes are limited, due to lack of understanding of molecular mechanisms controlling endothelial and fibroblastic homeostasis. We demonstrate here that the matrix receptor anthrax toxin receptor 1 (ANTXR1), also known as tumor endothelial marker 8 (TEM8), is an essential...

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Source

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Identifiers

PMID: 25572963
DOI: 10.1016/j.matbio.2014.12.002
PMCID: PMC4409530

Genes

MMP2
ANTXR1
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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