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Article

Anthrax toxin: receptor binding, internalization, pore formation, and translocation.

Annual review of biochemistry - 1 Jan 2007

Young John A T, Collier R John

Abstract excerpt

Anthrax toxin consists of three nontoxic proteins that self-assemble at the surface of receptor-bearing mammalian cells or in solution, yielding a series of toxic complexes. Two of the proteins, called Lethal Factor (LF) and Edema Factor (EF), are enzymes that act on cytosolic substrates. The third, termed Protective Antigen (PA), is a multifunctional protein that binds to receptors, orchestrates the assembly and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17335404
DOI: 10.1146/annurev.biochem.75.103004.142728

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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