Article

Modeling nascent transcription from chromatin landscape and structure

2024-06-06

Abstract excerpt

Different cell types and their associated functionalities emerge from a single genomic sequence when certain regions are expressed while others remain silenced. Modeling gene expression and its potential malfunctioning in different cellular contexts is hence pivotal to understand both development and disease. We present the Chromatin Landscape and Structure to Expression Regressor (CLASTER), an epigenetic-based de...

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Literature Corpus work: f7546e59-70e6-5e14-8ab1-becf605fb8c1
DOI: 10.1101/2024.06.04.597340

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