Article

HSeeker: an algorithm for systematic H-DNA sequence identification

2026-07-16

Abstract excerpt

H-DNA is a naturally occurring intramolecular DNA triplex structure formed by Hoogsteen hydrogen bonds at homopurine-homopyrimidine mirror repeats and has functional roles in gene regulation, genome instability, and human disease. The existing H-DNA detection tools capture only a subset of H-DNA sequences, often missing relevant sequence features or failing to assess key aspects of structural stability. To address...

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Literature Corpus work: f6aab129-a605-50e4-b82b-6f5217d67a19
DOI: 10.64898/2026.07.10.737678

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