Article

Human genomic DNA is widely interspersed with i-motif structures

2022-04-14

Abstract excerpt

DNA i-motif structures are formed in the nucleus of human cells and are believed to provide critical genomic regulation. While the existence of i-motif structures in human cells has been demonstrated by immunofluorescent staining and by characterisation of select model genes, the abundance and distribution of such structures in the human genome has remained unclear. Here we utilize high affinity i-motif immunoprec...

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Literature Corpus work: 3716664a-b41a-576b-8e5f-0952c2e467e8
DOI: 10.1101/2022.04.14.488274

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