Article

Mutagenesis at non-B DNA motifs in the human genome: a course correction

2022-02-09

Abstract excerpt

Non-B DNA structures formed by repetitive sequence motifs are known instigators of mutagenesis in experimental systems. Analyzing this phenomenon computationally in the human genome requires careful disentangling of intrinsic confounding factors, including overlapping and interrupted motifs, and recurrent sequencing errors. Accounting for these factors eliminates all signals of repeat-induced mutagenesis that exte...

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Literature Corpus work: 058099ba-8a96-5c2d-a90c-425763011687
DOI: 10.1101/2022.02.08.479604

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