Article

ZSeeker: An optimized algorithm for Z-DNA detection in genomic sequences

2025-02-10

Abstract excerpt

Z-DNA is an alternative left-handed helical form of DNA with a zigzag-shaped backbone that differs from the right-handed canonical B-DNA helix. Z-DNA has been implicated in various biological processes, including transcription, replication, and DNA repair, and can induce genetic instability. Repetitive sequences of alternating purines and pyrimidines have the potential to adopt Z-DNA structures. ZSeeker is a novel...

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Literature Corpus work: 4c44f89a-a940-5e24-b6f8-f11571acfa8a
DOI: 10.1101/2025.02.07.637205

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