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Linking Dynamic DNA Secondary Structures to Genome Instability

2022-01-20

Abstract excerpt

<h4>Summary</h4> Genomic double-stranded DNA (dsDNA) becomes single-stranded (ssDNA) during replication, transcription, and DNA repair. ssDNA is therefore believed to be transient, occurring in only a fraction of the genome at a given time, and variable amongst a population of cells. These transiently formed ssDNA segments can also adopt alternative, dynamic DNA conformations, such as cruciform DNA, triplexes, qu...

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Literature Corpus work
20b728c3-643a-559b-be6a-17c90a32c9fd
DOI
10.1101/2022.01.19.476973
Open publication

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Linking Dynamic DNA Secondary Structures to Genome InstabilityDOI 10.1101/2022.01.19.476973
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