Article

Single-virion Sequencing of Lamivudine Treated HBV Populations Reveal Population Evolution Dynamics and Demographic History

2017-04-20

Abstract excerpt

Viral populations are complex, dynamic, and fast evolving. The evolution of groups of closely related viruses in a competitive environment is termed quasispecies. To fully understand the role that quasispecies play in viral evolution, characterizing the trajectories of viral genotypes in an evolving population is the key. In particular, long-range haplotype information for thousands of individual viruses is critic...

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Literature Corpus work: f6579e38-553d-59ff-8a59-2472025c508d
DOI: 10.1101/129023

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